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p jak 1  (Santa Cruz Biotechnology)


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    Santa Cruz Biotechnology p jak 1
    P Jak 1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 4347 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p jak 1/product/Santa Cruz Biotechnology
    Average 96 stars, based on 4347 article reviews
    p jak 1 - by Bioz Stars, 2026-03
    96/100 stars

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    rhIL-13 inhibited HUVECs migration via the JAK-1/STAT-3 signaling pathway. (a) rhIL-13 regulated the activation of the JAK-1/STAT-3 signaling pathway. ** p < .01 vs. Ctrl; ## p < .01 vs. rhIL-13. (b) the co-application of stattic and rhIL-13 inhibited the rhIL-13 induced inhibition of cell migration in cultured HUVECs. ** p < .01 vs. Ctrl; ## p < .01 vs. rhIL-13. Scale bars: 200 μm. (c) STAT-3 inhibition eliminated the accumulation of ROS induced by rhIL-13. ** p < .01 vs. Ctrl; ## p < .01 vs. rhIL-13. Scale bars: 200 μm. The results were derived from 3 independent experiments each performed in duplicate. Data represent the mean±SD. Control, Ctrl. Negative control, NC. Ruxolitinib, Rux. Stattic, Stt.

    Journal: Cell Adhesion & Migration

    Article Title: IL-13 neutralization attenuates carotid artery intimal hyperplasia and increases endothelial cell migration via modulating the JAK-1/STAT-3 signaling pathway

    doi: 10.1080/19336918.2023.2265158

    Figure Lengend Snippet: rhIL-13 inhibited HUVECs migration via the JAK-1/STAT-3 signaling pathway. (a) rhIL-13 regulated the activation of the JAK-1/STAT-3 signaling pathway. ** p < .01 vs. Ctrl; ## p < .01 vs. rhIL-13. (b) the co-application of stattic and rhIL-13 inhibited the rhIL-13 induced inhibition of cell migration in cultured HUVECs. ** p < .01 vs. Ctrl; ## p < .01 vs. rhIL-13. Scale bars: 200 μm. (c) STAT-3 inhibition eliminated the accumulation of ROS induced by rhIL-13. ** p < .01 vs. Ctrl; ## p < .01 vs. rhIL-13. Scale bars: 200 μm. The results were derived from 3 independent experiments each performed in duplicate. Data represent the mean±SD. Control, Ctrl. Negative control, NC. Ruxolitinib, Rux. Stattic, Stt.

    Article Snippet: Then incubated with the primary antibodies against p-JAK-1 (Cat#GB114584, Servicebio, China), p-STAT-3 (Cat#381552, ZenBio, China), NOX-4 (Cat#380874, ZenBio, China) and GAPDH (Cat#GB15002, Servicebio, China).

    Techniques: Migration, Activation Assay, Inhibition, Cell Culture, Derivative Assay, Negative Control